Is there a better "Big Bang" duo than Sheldon and Penny? They never dated, but Sheldon and Penny’s friendship is one of the most important relationships of the entire series.
A lot of bad things happend to Sheldon on "The Big Bang Theory." For this list, we’ll be looking at the times the others pushed Sheldon’s buttons (deservingly o not) so much that we actually felt sorry for him.
![Sheldon Cooper :]](http://images5.fanpop.com/image/photos/24600000/Sheldon-Cooper-sheldon-cooper-24678236-500-400.jpg)
