Carlisle lived in London. He was the son a pastor. His father hunted vampiros and other creatures. As his father grew older, Carlisle took over his work and was bitten por a vampire. Because although his father was más obsessive, Carlisle found real vampires. Unlike his dad. So... he was changed in the age of 23 around 1663.
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Oh... and if tu want to know more: tu can have a look at this link