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In 1971, John List left a note with the bodies of his mother, wife and three children in his mansion ballroom right before he disappeared. Eighteen years later, all detectives had to work from is an outdated photograph of List.

Alarmingly high levels of thyroid hormones pump through the systems of South Dakota residents. Investigators study one family who all got sick, except their 12-year-old son who is a vegetarian.

Between 1985 and 1988, 18 people were choked, molested and left for dead in the remote desert mountains of California. The only witnesses were the insects, who played an important role in solving the crimes.

On the night of May 22, 1992, Betty Wilson returned home after a meeting. She walked up the stairs to the bedroom and discovered her husband, lying in a pool of blood.

When 180 Legionnaires contract pneumonia-like symptoms after a Philadelphia Convention and 29 of them die, doctors and scientists are mystified.

The U.S. criminal justice system's first use of DNA profiling in a serial murder case frees an innocent man after he spent two years in prison, and convicts a real killer.

Early one morning in a deserted area outside of Phoenix, a motorcyclist discovered the body of a young woman. She had been beaten, bound, strangled and possibly raped.

Forensic Files - Season 1, Ep 3: The House That Roared

A woman disappeared and her husband became the prime suspect -- especially after police found a huge bloodstain on the carpet of their bedroom.

A fifteen-year-old boy died from a mysterious gunshot wound to his head while he was sitting in the lobby of his father's gun club.

Forensic Files - Series Premiere: The Disappearance of Helle Crafts

A Connecticut flight attendant went missing and was never seen again. Police suspected her husband was guilty of murder, and they were able to prove it - even though they never found the woman's body.

On May 3, 2007, four-year-old Madeleine McCann went missing while on vacation with her family in Portugal. At the time of her disappearance, her parents—Kate and Gerry McCann—were dining just 60 yards away from Madeleine’s bedroom.

Bride-to-Be Vanishes 3 Weeks Before Wedding - Crime Watch Daily with Chris Hansen

Niqui McCown was about to get married when she vanished after heading to a laundromat. Was she a runaway bride, or was something more sinister behind her disappearance?

Why did Henri van Breda murder his family? | 60 Minutes Australia

23-year-old Henri van Breda was found guilty of killing his family and will spend the rest of his life locked up. But there’s one person who’s not so convinced. Danielle Janse Van Rensburg tells 60 Minutes her boyfriend is not a killer.

Do clues point to an intruder in Darlie Routier case?