Even though they're madly in love, their relationship is just too complicated. They both need space to figure out what they want and if they're really meant for each other.

Of course they are going to break up. Then the beginning or middle of next season they will get back together.

I think they'll leave their relationship hanging, indicating that they're gonna break up or need some space... but its definetly not over over. I wonder if there will be any adultery in this episode.

I doubt their relationship will ever be over but they need space from each other right now.

They will break up, because both of them haven't got there life's together, and they can't deal with a relationship and all that stuff that comes along with a relationship, so they break up.

they better not!!! derek is being a jerk!!!!

Ouch 50/50 right now!

the hopeful side of me pick no because I love them and they love eachother but I do think they will it hanging in the end because it's grey's hehe... I totally agree with everybody, of course if were up to me they would just ignore all their issues and just be blissfully happy..;-)

if they break up i am going to kill myself because they need to stay together its basicaly the show well in a way

there love story has been going on forever. since season one.
i'm tired of it already.

<<<They are not gonna break up. I've already seen it.>>>

they flipping better not (haven't seen it yet :( )

i have to wait 3 more episodes before the season finale!!!but they shouldn't break up! they really should be together !!

noooo they cant they were made for each other
if they do i will cry but they already broke up but still had sumthin there

I HOPE SO!

okay well they're not cuz they are just about to get back together..so...yes. And i dont think they'll break up again cuz Shonda is putting them together..YAY!!

i don't think so...i really don't
but i'm sure that shonda will get them together for good

hopefully not!

This pick was meant for last Season LOL!

no!

No way ;)

There relationship is complicated, but they are destined to be together. I hope they never break up. and if they do i hope they realize how much they love each other.

becaus if they did it will be vrey stupied

god i hope not!!!

Derek and Meredith's relationship is the main focus of the show.

No she will have a little McDreamy and Addison will deliver the baby under massive proportion. Maybe during a hurricane or something.

Meredith will give birth to McDreamy Junior and Addison will deliver their McBaby.

I don't hope so!

They make such a good couple

I hope their is a complication and they need Addison to deliver the baby
They will last forever