Hmm... The first one who comes to mind is Holo from Spice and Wolf. I think she's part lobo o is a lobo in disguise o something. (I haven't seen the mostrar in a really long time)
Zakuro Fujiwara from Tokyo Mew Mew. She is infused with the DNA of a grey lobo and even though she is a bit of a bitch, (pun not intended) she is very elegant and I can sometimes understand why mint likes her so much.
he ate the lobo lobo frutas (Devil Fruit) so he can turn to lobo when ever he wants and have all the powers of a wolf...........he is funny....but also very cunning as a wolf.........he he he he he